Guys should know the mechanism behind erection. Testosterone is a primary male harmone necessary for sex drive and also secondary male characteristics. It is also necessary for sperm production. Testosterone levels can easily be assisted from a simple blood test. The normal values of testosterone in males is 437 to 707 ng/dl while in females 24 to 47 ng/dl. 1 ng(nano gram)=10-3 mcg(micro gram);1 mcg=10-6 g; dl-deci liter= 10-1 l.
Body releases the chemical molecule 'nitric oxide(NO)' to create an erection. This molecule acts on another enzyme within the blood vessels of the erectile tissue accumulating another chemical called cyclic GMP(guanosine mono phosphate). This accumulation makes calcium leave the blood vessel walls and the walls relax. Blood fills the blood vessels and they become engorged, acting like a flap valves closing off the outflow of blood. Hence erection results. Finally the body releases another chemical called phosphodiesterase-5, which reverses the process. That is, it reduces the accumulation of cyclic GMP thus by bringing erection to an end. The pill Viagra(Sildenafil) basically inactivates the erection ending chemical phosphodiesterase-5 (PDE5).
The pill was developed in Pfizer labs and was being tested to lower blood pressure. Medical residents were the volunteers for the study and they didn't find any change in their blood pressure and they were asked to return the unused pill. But they were reluctant to return the unused pills as they were experiencing enhanced erections:-) So, the pill was accidentally discovered and it does wonders in most ED(erectile dysfunction) related cases. Only if the pill doesn't work or works erratically, then further investigation becomes necessary.
The pill is available in 25mg, 50mg, 100mg tablets. Normally it is effective when taken with water on an empty stomach, 3-4 hours after a meal. The pill will work only when there is sufficient sexual stimulation. Just because the guy is bored and swallows a pill , without sexual stimulation and screams & complains 'i don't have erection', the pill is not the problem:-) It works upto 8 hours after it is taken and allows a man to respond to sexual stimulation. In rare cases, everything may appear to have blue tinge for 30 mnts to 90 mnts. Normally, it is safe and doesn't have dangerous side effects. Other drugs prescribed for ED are Cialis(tadalafil) & Nuviva(vardanafil).
Viagra shouldn't be taken with nitrates(nitro glycerin type drugs) prescribed for angina in men. It can be lethal. Infact in one study, they found that viagra, given to men with angina, right before coronary bypass surgery, improved blood flow to the heart. As long as viagra is not mixed with nitrates, men with ED can use it safely. Since ED is mainly psychological based, it is better not to stress out too much. This explains why the infertility rate has increased quite a bit in the last 10 years. Stress affects Testosterone levels -> low sperm count -> infertility. Remember, Life is Beautiful :-)
Please read this interesting article 'Joy of Uncircumcising', first appeared in the British Medical Journal in 1994. Circumcision is probably & still carried out in some communities???...
http://www.cirp.org/pages/reviews/bigelow/
